Обзорная статья

Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications

Arun KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, IndiaMirkomil SharipovDepartment of Chemistry, Changwon National University, Changwon 51140, KoreaА. С. ТураевLaboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, Tashkent 100125, UzbekistanShavkatjon AzizovDepartment of Pharmaceutical Chemistry, Tashkent Pharmaceutical Institute, Tashkent 100015, UzbekistanIsmatdjan AzizovState Center for Expertise and Standardization of Medicines, Medical Devices, and Medical Equipment, State Unitary Enterprise, Tashkent 100002, UzbekistanEdwin MakhadoDepartment of Chemistry, School of Physical and Mineral Sciences, University of Limpopo, Polokwane 0727, South AfricaAbbas RahdarDepartment of Physics, Faculty of Science, University of Zabol, Zabol 538-98615, IranDeepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, IndiaSadanand PandeyDepartment of Chemistry, College of Natural Sciences, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Korea

Polymersjournal2022en

ABI

Аннотация

Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs)provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy.

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Темы

Nanoparticle-Based Drug Delivery Nanoplatforms for cancer theranostics RNA Interference and Gene Delivery

Идентификаторы

DOI: 10.3390/polym14153027

Цитирования и источники

Цитирований: 1 Использованных источников: 118

Показатели — AkademScholar