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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

Joseph A. FraiettaCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USASimon F. LaceyCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAElena J. OrlandoNovartis Institutes for BioMedical Research, Cambridge, MA, USAIulian Pruteanu-MaliniciNovartis Institutes for BioMedical Research, Cambridge, MA, USAMercy GohilCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAStefan LundhCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAAlina C. BoesteanuCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAYan WangCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USARoddy S. O’ConnorCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAWei‐Ting HwangDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USAEdward PequignotCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USADavid E AmbroseCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAChangfeng ZhangCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USANicholas S. WilcoxCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAFelipe BedoyaCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USACorin L. DorfmeierCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAChen FangCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USALifeng TianCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAHarit ParakandiCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAMinnal GuptaCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USARegina M. YoungCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAF. Brad JohnsonDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USAIrina KulikovskayaCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USALi LiuCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAJun XuCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USASadik H. KassimNovartis Institutes for BioMedical Research, Cambridge, MA, USAMegan M. DavisCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USABruce L. LevineCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USANoelle V. FreyCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USADonald L. SiegelCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAAlexander C. HuangDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAE. John WherryDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAHans BitterNovartis Institutes for BioMedical Research, Cambridge, MA, USAJennifer L. BrogdonNovartis Institutes for BioMedical Research, Cambridge, MA, USADavid L. PorterDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USACarl H. JuneCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USAJ. Joseph MelenhorstCenter for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA. [email protected]
2018en
ABI

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