A new antimicrobial sesquiterpene isolated from endophytic fungus <i>Cytospora</i> sp. from the Chinese mangrove plant <i>Ceriops tagal</i>
Qin DengKey Laboratory of Tropical Biological Resources of Ministry of Education, Institute of Tropical Agriculture and Forestry, Hainan University, Haikou, P. R. China;Gang LiKey Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education, College of Material and Chemical Engineering, Hainan University, Haikou, P. R. ChinaMengyu SunKey Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education, College of Material and Chemical Engineering, Hainan University, Haikou, P. R. ChinaXiaobo YangKey Laboratory of Tropical Biological Resources of Ministry of Education, Institute of Tropical Agriculture and Forestry, Hainan University, Haikou, P. R. China;Jing XuKey Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education, College of Material and Chemical Engineering, Hainan University, Haikou, P. R. China
2018en
ABI
Аннотация
Chemical examination of Chinese mangrove Ceriops tagal endophytic Cytospora sp., yielded a new biscyclic sesquiterpene seiricardine D (1), and eight known metabolites, xylariterpenoid A (2a), xylariterpenoid B (2b) and regiolone (3) 4-hydroxyphenethyl alcohol (4), (22E, 24R)5, 8-epidioxy-5α, 8α-ergosta-6,22E-dien-3ß-ol (5), (22E, 24R)5, 8-epidioxy-5α, 8α-ergosta-6,9(11), 22-trien-3 ß-ol (6), ß-sitosterol (7) and stigmast-4-en-3-one (8). These structures were unambiguously elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. The antimicrobial activities of compounds 1–8 and their effects on a panel of plant and human pathogens were evaluated.
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