Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein‐Resistant Polymeric Coatings
Ivan ŘehořInstitute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.czHana MackováInstitute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410Sergey K. FilippovInstitute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410Jan KučkaInstitute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410Vladimír ProksInstitute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410Jitka ŠlegerováInstitute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.czStuart TurnerEMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)Gustaaf Van TendelooEMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)M LedvinaInstitute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.czMartin HrubýInstitute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410Petr CíglerInstitute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz
2013en
ABI
Аннотация
The novel synthesis of a polymeric interface grown from the surface of bright fluorescent nanodiamonds is reported. The polymer enables bioorthogonal attachment of various molecules by click chemistry; the particles are resistant to nonspecific protein adsorption and show outstanding colloidal stability in buffers and biological media. The coating fully preserves the unique optical properties of the nitrogen-vacancy centers that are crucial for bioimaging and sensoric applications.
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