Progress in the Studies on Rutaecarpine
Seung Ho LeeCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaJong‐Keun SonCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaByeong Seon JeongCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaTae‐Cheon JeongCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaHyeon Wook ChangCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaEung-Seok LeeCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 KoreaYurngdong JahngCollege of Pharmacy, Yeungnam University, Gyeongsan 712-749 Korea
2008en
ABI
Аннотация
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed.
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