Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life
Lukas WestermannDepartment of Medicine, Renal Division, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, GermanyBjörn NeubauerDepartment of Medicine, Renal Division, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, GermanyMichael KöttgenCIBSS - Centre for Integrative Biological Signalling Studies, Freiburg, Germany. [email protected]
2020en
ABI
Аннотация
Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly and constitutes the third highest risk factor for dementia. Lifetime noise exposure, genetic predispositions for degeneration, and metabolic stress are assumed to be the major causes of ARHL. Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel K
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