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Quercetin, Inflammation and Immunity

Yao LiInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaJiaying YaoInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaChunyan HanInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaJiaxin YangInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaMaria ChaudhryInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaShengnan WangInstitute of Animal Nutrition, Northeast Agricultural University, Harbin 150030, ChinaHongnan LiuScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central China, Ministry of Agriculture, Hunan Provincial Engineering Research Center of Healthy, Livestock, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical, Agriculture, Chinese Academy of Sciences, Changsha 410125, ChinaYulong YinScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central China, Ministry of Agriculture, Hunan Provincial Engineering Research Center of Healthy, Livestock, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical, Agriculture, Chinese Academy of Sciences, Changsha 410125, China
2016en
ABI

Аннотация

In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. This review focuses on the physicochemical properties, dietary sources, absorption, bioavailability and metabolism of quercetin, especially main effects of quercetin on inflammation and immune function. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Nevertheless, further studies are needed to better characterize the mechanisms of action underlying the beneficial effects of quercetin on inflammation and immunity.

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