Статья

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, IranLaura MachínInstitute of Pharmacy and Food, University of Havana, Havana, CubaLianet MonzoteParasitology Department, Institute of Medicine Tropical Pedro Kourí, Havana, CubaJavad Sharifi‐RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, IranShahira M. EzzatDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, EgyptMohamed A. SalemDepartment of Pharmacognosy, Faculty of Pharmacy, Menoufia University, Gamal Abd El Nasr st., Shibin Elkom, Menoufia 32511, EgyptRana M. MerghanyDepartment of Pharmacognosy, National Research Centre, Giza 12622, EgyptNihal M. El MahdyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6th of October 12566, EgyptCeyda Sibel KılıçDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara 06100, TurkeyOksana SytarDepartment of Plant Biology Department, Institute of Biology, Taras Shevchenko National University of Kyiv, Volodymyrska str., 64, Kyiv 01033, UkraineMehdi Sharifi‐RadDepartment of Medical Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, IranFarukh SharopovDepartment of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, TajikistanNatália MartinsFaculty of Medicine, University of Porto, Porto 4200-319, PortugalMiquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, Concepción 4070386, ChileWilliam C. ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong

2020en

ABI

Аннотация

Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.

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Идентификаторы

DOI: 10.1021/acsomega.0c01818

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar