Статья

Anti‐Inflammatory, Antioxidant and Enzyme Inhibition Activities in Correlation with Mycochemical Profile of Selected Indigenous <i>Ganoderma</i> spp. from Balkan Region (Serbia)

Milena RašetaDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad SerbiaMira PopovićDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad SerbiaIvana BearaDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad SerbiaFilip ŠibulDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad SerbiaGökhan ZenginDepartment of Biology, Science Faculty Selcuk University Alaeddin Keykubat Yerleskesi Selcuklu 42130 Konya TurkeySanja VlaisavljevićDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad SerbiaMaja KaramanDepartment of Biology and Ecology, Faculty of Sciences University of Novi Sad Trg D. Obradovića 2 21000 Novi Sad Serbia

2020en

ABI

Аннотация

Abstract The aim of this research work was to study the bioactivity potentials (antioxidant, anti‐inflammatory, and enzyme inhibitory) of ethanol (EtOH), water (H 2 O) and chloroform (CHCl 3 ) extracts of G. applanatum , G. lucidum , G. pfeifferi and G. resinaceum as well as their mycochemical profile: the total content of phenolics (TP) and sugars (TS) and LC/MS/MS detection of phenolics. LC/MS/MS profile showed that p‐ hydroxybenzoic and protocatechuic acids were mostly found. The highest ABTS and DPPH activities were detected in polar G. applanatum extracts (159.84±0.59 mg TE/g d.w., IC 50 =0.85±0.30 μg/mL, respectively), while G. resinaceum CHCl 3 extract was the most potent in NO assay (IC 50 =41.21±0.18−81.89±0.81 μg/mL). The highest TP and TS were generally determined in G. applanatum EtOH extracts. Enzyme inhibitory effects were determined in H 2 O extracts. Generally, CHCl 3 extracts showed the most powerful anti‐inflammatory potential. These results suggest that analyzed species are a promising source of bioactive compounds and may be considered as candidates for new food supplements or drug formulations.

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Идентификаторы

DOI: 10.1002/cbdv.202000828

Цитирования и источники

Цитирований: 4Использованных источников: 0

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