Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
Jong‐Ho ChaDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul 151-742, KoreaWenhao YangDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAWeiya XiaDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAYongkun WeiDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USALi-Chuan ChanDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, University of Texas Health Science Center, Houston, TX 77030, USASeung‐Oe LimDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAChia-Wei LiDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USATae‐Wan KimDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAShih-Shin ChangDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAHeng‐Huan LeeDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAJennifer L. HsuDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 413, TaiwanHung-Ling WangGraduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, TaiwanChu‐Wei KuoInstitute of Biological Chemistry, Academia Sinica, Nankang, Taipei 115, TaiwanWei‐Chao ChangGraduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, Taiwan; Genomics Research Center, Academia Sinica, Nankang, Taipei 115, TaiwanSirwan HadadDepartment of Surgery, University of Sheffield, Western Bank, Sheffield S10 2TN, UKColin A. PurdieDepartment of Pathology, Ninewells Hospital and Medical School, Dundee DD1 9SY, UKAaron McCoyDepartment of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAShirong CaiDepartment of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAYizheng TuDepartment of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAJennifer K. LittonDepartment of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAElizabeth A. MittendorfDepartment of Breast Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAStacy MoulderDepartment of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAW. Fraser SymmansDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAAlastair M. ThompsonDepartment of Breast Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAHelen Piwnica‐WormsDepartment of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, University of Texas Health Science Center, Houston, TX 77030, USAChung‐Hsuan ChenGenomics Research Center, Academia Sinica, Nankang, Taipei 115, TaiwanKay‐Hooi KhooInstitute of Biological Chemistry, Academia Sinica, Nankang, Taipei 115, TaiwanMien‐Chie HungDepartment of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, University of Texas Health Science Center, Houston, TX 77030, USA; Graduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 413, Taiwan. Electronic address: [email protected]
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