Статья

Ordered Mesoporous Bioactive Glasses for Bone Tissue Regeneration

Adolfo López‐NoriegaDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, SwedenDaniel ArcosDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, SwedenIsabel Izquierdo‐BarbaDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, SwedenYasuhiro SakamotoDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, SwedenOsamu TerasakiDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, SwedenMaría Vallet‐RegíDepartamento Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain, and Stockholm University, Arrhenius Lab, S-10691 Stockholm, Sweden

2006en

ABI

Аннотация

A series of ordered mesoporous SiO2−CaO−P2O5 sol−gel glasses which are highly bioactive has been synthesized through evaporation-induced self-assembly in the presence of a nonionic triblock copolymer, EO20PO70EO20 (P123), template. By keeping constant the SiO2 + P2O5/P123 ratio, the influence of the CaO precursor, Ca(NO3)2·4H2O, on the mesostructure has been determined. After calcination at 700 °C, ordered mesoporous glasses are obtained, showing structures that evolve from 3D-cubic to 2D-hexagonal when the CaO content increases. The mesoporous glasses are highly bioactive compared with conventional ones, due to the increased textural characteristics supplied by the template. The bioactivity tests point out that the surface area, porosity, and 3D-structure become more important than chemical composition during the apatite crystallization stage in these materials, due to the very high textural parameters obtained.

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Идентификаторы

DOI: 10.1021/cm060488o

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar