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Artificial Intelligence (AI) Applications in Drug Discovery and Drug Delivery: Revolutionizing Personalized Medicine

Dolores R. SerranoDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainFrancis C. LucianoDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainBrayan J. AnayaDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainBaris ÖngorenDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainAytug KaraDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainGracia MolinaDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainBianca I. RamirezDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainSergio A. Sánchez-GuiralesDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainJJ Martínez SimónDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainGreta TomiettoDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainChrysi RaptiDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainHelga K. RuizDepartment of Pharmaceutics and Food Science, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, SpainSatyavati RawatDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi 221005, IndiaDinesh KumarDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi 221005, IndiaAikaterini LalatsaCRUK Formulation Unit, School of Pharmacy and Biomedical Sciences, University of Strathclyde, 161, Cathedral Street, Glasgow G4 0RE, UK
2024en
ABI

Аннотация

Artificial intelligence (AI) encompasses a broad spectrum of techniques that have been utilized by pharmaceutical companies for decades, including machine learning, deep learning, and other advanced computational methods. These innovations have unlocked unprecedented opportunities for the acceleration of drug discovery and delivery, the optimization of treatment regimens, and the improvement of patient outcomes. AI is swiftly transforming the pharmaceutical industry, revolutionizing everything from drug development and discovery to personalized medicine, including target identification and validation, selection of excipients, prediction of the synthetic route, supply chain optimization, monitoring during continuous manufacturing processes, or predictive maintenance, among others. While the integration of AI promises to enhance efficiency, reduce costs, and improve both medicines and patient health, it also raises important questions from a regulatory point of view. In this review article, we will present a comprehensive overview of AI's applications in the pharmaceutical industry, covering areas such as drug discovery, target optimization, personalized medicine, drug safety, and more. By analyzing current research trends and case studies, we aim to shed light on AI's transformative impact on the pharmaceutical industry and its broader implications for healthcare.

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