Nickel‐Catalyzed Solvent‐Free Three‐Component Coupling of Aldehyde, Alkyne and Amine

Abstract A versatile three‐component coupling of aldehydes, alkynes and amines has been developed, catalyzed by Ni 2+ ‐exchanged Y‐zeolite, which acts as an environmentally benign, recyclable, efficient and heterogeneous catalyst. This three‐component (A 3 ) coupling (reported for the first time to proceed under nickel catalysis) is carried out under solvent‐free conditions, and the corresponding propargylamines are obtained in good to excellent yields.

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