Determination of aflatoxin M1 using an aptamer-based biosensor immobilized on the surface of dendritic fibrous nano-silica functionalized by amine groups
Houman Kholafazad KordashtDepartment of Food Hygiene and Aquatics, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, IranMir‐Hassan MoosavyDepartment of Food Hygiene and Aquatics, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, IranMohammad HasanzadehDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, IranJafar SoleymaniPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, IranAhad MokhtarzadehImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2019en
ABI
Аннотация
-Tb. The engineered aptasensor demonstrated excellent behaviour toward the determination of AF M1, where the low limit of quantification was 10 fM. The proposed aptamer-based bioassay was successfully used for the monitoring of AF M1 in milk samples. This work provides a beneficial reference for the sensing of other toxins in food/pharmaceutical assays and veterinary medicine.
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