Статья

Oncoviruses: Induction of cancer development and metastasis by increasing anoikis resistance

Zahra Sobhi AmjadDepartment of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, IranAli ShojaeianResearch Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, IranJavid Sadri NahandInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranMobina BayatInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranMohammad TaghizadiehDepartment of Pathology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranMosayeb RostamianNosocomial Infections Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranFarhad BabaeiDepartment of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, IranMohsen MoghoofeiDepartment of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

2023en

ABI

Аннотация

The phenomenon of cell death is a vital aspect in the regulation of aberrant cells such as cancer cells. Anoikis is a kind of cell death that occurs when cells get separated from the extracellular matrix. Some cancer cells can inhibit anoikis in order to progress metastasis. One of the key variables that might be implicated in anoikis resistance (AR) is viral infections. The most important viruses involved in this process are Epstein-Barr virus, human papillomavirus, hepatitis B virus, human herpes virus 8, human T-cell lymphotropic virus type 1, and hepatitis C virus. A better understanding of how carcinogenic viruses suppress anoikis might be helpful in developing an effective treatment for virus-associated cancers. In the current study, we review the role of the mentioned viruses and their gene products in anoikis inhibition.

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Идентификаторы

DOI: 10.1016/j.heliyon.2023.e22598

Цитирования и источники

Цитирований: 6Использованных источников: 0

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