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Cytotoxicity Assessment of Ti–Al–C Based MAX Phases and Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXenes on Human Fibroblasts and Cervical Cancer Cells

Błażej ScheibeNanoBioMedical Centre, Adam Mickiewicz University, 61 614 Poznań, PolandJacek K. WychowaniecSchool of Chemistry, University College Dublin, Belfield, Dublin 4, IrelandMagdalena ScheibeRegional Centre for Advanced Technologies and Materials, Palacký University Olomouc, 771 46 Olomouc, Czech RepublicBarbara PeplińskaNanoBioMedical Centre, Adam Mickiewicz University, 61 614 Poznań, PolandMarcin JarekNanoBioMedical Centre, Adam Mickiewicz University, 61 614 Poznań, PolandGrzegorz NowaczykNanoBioMedical Centre, Adam Mickiewicz University, 61 614 Poznań, PolandŁucja PrzysieckaNanoBioMedical Centre, Adam Mickiewicz University, 61 614 Poznań, Poland
2019en
ABI

Аннотация

forms remained safe to MSU1.1 cells with only slight cytotoxic behavior in the highest concentration regime. The cytotoxic behavior was also cell-type dependent, with higher cytotoxicities observed for cells of cancer origin. Finally, the cell response toward multilayered MXenes in an in vitro system, using scanning electron microscopy was depictured. Our work increases understanding of the safe use of MXene materials and points toward their possible use in fields spanning from energy storage systems to medical devices.

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