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Comparative Study of Physicochemical and Antibacterial Properties of ZnO Nanoparticles Prepared by Laser Ablation of Zn Target in Water and Air

E. A. GavrilenkoSiberian Physical Technical Institute, Tomsk State University, Lenina, 36, Tomsk 634050, RussiaDaria A. GoncharovaSiberian Physical Technical Institute, Tomsk State University, Lenina, 36, Tomsk 634050, RussiaИ. Н. ЛапинSiberian Physical Technical Institute, Tomsk State University, Lenina, 36, Tomsk 634050, RussiaAnna L. NemoykinaLaboratory of Biopolymers and Biotechnology, Tomsk State University, Lenina, 36, Tomsk 634050, RussiaВ. А. СветличныйSiberian Physical Technical Institute, Tomsk State University, Lenina, 36, Tomsk 634050, RussiaAli A. AljulaihDepartment of Mechanical Engineering, Tokai University, Hiratsuka, Kanagawa 259-1259, JapanNeli MintchevaDepartment of Chemistry, University of Mining and Geology, 1700 Sofia, BulgariaSergei A. KulinichDepartment of Mechanical Engineering, Tokai University, Hiratsuka, Kanagawa 259-1259, Japan
2019en
ABI

Аннотация

Here, we report on ZnO nanoparticles (NPs) generated by nanosecond pulsed laser (Nd:YAG, 1064 nm) through ablation of metallic Zn target in water and air and their comparative analysis as potential nanomaterials for biomedical applications. The prepared nanomaterials were carefully characterized in terms of their structure, composition, morphology and defects. It was found that in addition to the main wurtzite ZnO phase, which is conventionally prepared and reported by others, the sample laser generated in air also contained some amount of monoclinic zinc hydroxynitrate. Both nanomaterials were then used to modify model wound dressings based on biodegradable poly l-lactic acid. The as-prepared model dressings were tested as biomedical materials with bactericidal properties towards S. aureus and E. coli strains. The advantages of the NPs prepared in air over their counterparts generated in water found in this work are discussed.

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