Apollo: a sequence annotation editor
SE LewisDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USASMJ SearleWellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UKNomi L. HarrisFlyBase-Berkeley, University of California, Berkeley, CA, 94720-3200, USAMark S. GibsonDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USAV IyerWellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UKJ RichterHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USAC. van der WielDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USALeyla BayraktarogluFlyBase-Harvard, Department of Molecular and Cell Biology, Harvard University, Biological Laboratories, 16 Divinity Avenue, Cambridge, MA, 02138-2020, USAEwan BirneyEuropean Bioinformatics Institute, Hinxton, Cambridgeshire, CB10 1SD, UKMA CrosbyFlyBase-Harvard, Department of Molecular and Cell Biology, Harvard University, Biological Laboratories, 16 Divinity Avenue, Cambridge, MA, 02138-2020, USAJS KaminkerDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USABB MatthewsFlyBase-Harvard, Department of Molecular and Cell Biology, Harvard University, Biological Laboratories, 16 Divinity Avenue, Cambridge, MA, 02138-2020, USASE ProchnikDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USACD SmithDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USAJL TupyDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USAGerald M. RubinDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USASima MisraDepartment of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA, 94720-3200, USAChris MungallHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USAM. E. ClampWellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK
2002en
ABI
Аннотация
The well-established inaccuracy of purely computational methods for annotating genome sequences necessitates an interactive tool to allow biological experts to refine these approximations by viewing and independently evaluating the data supporting each annotation. Apollo was developed to meet this need, enabling curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome and it is increasingly being used as a starting point for the development of customized annotation editing tools for other genome projects.
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