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Tuberculosis, social determinants and co-morbidities (including HIV)

Raquel DuarteCentro Hospitalar Vila Nova de Gaia/Espinho EPE, Departamento de Pneumologia, Vila Nova de GaiaKnut LönnrothCentre for Epidemiology and Community MedicineCláudia CarvalhoServiço de Doenças Infecciosas, Centro Hospitalar São JoãoFrancisca Sabrina Vieira LimaCentro Hospitalar Vila Nova de Gaia/Espinho EPE, Departamento de Pneumologia, Vila Nova de GaiaAna Cláudia CarvalhoLaboratory of Innovations in Therapies, Education and Bioproducts (LITEB), Oswaldo Cruz Institute (IOC), FioCruzMarcela Muñóz-TorricoClínica de Tuberculosis, Instituto Nacional de Enfermedades RespiratoriasRosella CentisWHO Collaborating Centre for TB and Lung Diseases, Maugeri Institute, IRCCS Tradate
2017en
ABI

Аннотация

The risk of exposure, progression to active tuberculosis (TB) and then to cure is a process affected by several risk factors. Along with well known risk factors such as human immunodeficiency virus (HIV), use of immunosuppressive drugs and being of young age, emerging risk factors such socio-economic and behavioral aspects play a significant role in increasing the susceptibility to infection, and unsuccessful treatment outcomes. This paper summarizes the effects of these socio-economic determinants and co-morbidities (including HIV) on TB infection and disease.

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