Статья

Characteristics of Probe Electrospray Generated from a Solid Needle

Lee Chuin ChenClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanKentaro NishidateClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanYuta SaitoClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanKunihiko MoriClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanDaiki AsakawaClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanSén TakedaUniversity of YamanashiTakeo KubotaClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanHirokazu HoriClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, JapanKenzo HiraokaClean Energy Research Center, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan, Department of Anatomy and Cell Biology and Department of Epigenetic Medicine, Faculty of Medicine, University of Yamanashi, Shimo-Kateau 1110, Chuo, 409-3898, Japan, and Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Takeda 4-3-11, Kofu 400-8511, Japan

2008en

ABI

Аннотация

Probe electrospray ionization (PESI) has recently been developed, in which the electrospray was generated from a solid needle instead of by using a capillary. In this paper, the characteristics of probe electrospray ionization were studied based on the measurement of spray current, optical microscopy, and PESI mass spectrometry. In the experiment, the solid needle was moved up and down a vertical axis, and a small amount of sample was repeatedly loaded to the needle when the tip of the needle touched the surface of the liquid sample at the lowest position. After the application of high voltage, a liquid droplet was formed on the tip of the solid needle probe, with its size was determined by the size of the needle tip. The liquid flow rate to the tip, as indicated by the spray current, depends on the voltage applied to the needle as well as the loaded liquid amount. Stable electrospray can be maintained until the total consumption of liquid sample. The kilohertz current pulsation takes place in the case of overloading the sample to the needle. The influences of the applied voltage and the liquid flow rate on the PESI mass spectra were also examined.

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Идентификаторы

DOI: 10.1021/jp803730x

Цитирования и источники

Цитирований: 4Использованных источников: 0

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