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GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy

S. JanDSV/I2BM/SHFJ, Commissariat à l'Energie Atomique, Orsay, FranceDidier BenoitIMNC–UMR 8165 CNRS–Paris 7 and Paris 11 Universities, 15 rue Georges Clémenceau, 91406 Orsay Cedex, FranceE. BechevaDSV/I2BM/SHFJ, Commissariat à l’Energie Atomique, Orsay, FranceThomas CarlierINSERM U892–Cancer Research Center, University of Nantes, Nantes, FranceF CassolCentre de physique des particules de Marseille, CNRS-IN2P3 and Université de la Méditerranée, Aix-Marseille II, 163, avenue de Luminy, 13288 Marseille Cedex 09, FrancePatrice DescourtINSERM, U650, Laboratoire du Traitement de l’Information Medicale (LaTIM), CHU Morvan, Brest, FranceT. FrissonUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, FranceLoïc GrevillotUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, FranceLaurent GuiguesUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, FranceLydia MaigneLaboratoire de Physique Corpusculaire, 24 Avenue des Landais, 63177 Aubière Cedex, FranceC. MorelCentre de physique des particules de Marseille, CNRS-IN2P3 and Université de la Méditerranée, Aix-Marseille II, 163, avenue de Luminy, 13288 Marseille Cedex 09, FranceY. PerrotLaboratoire de Physique Corpusculaire, 24 Avenue des Landais, 63177 Aubière Cedex, FranceNiklas RehfeldIMNC–UMR 8165 CNRS–Paris 7 and Paris 11 Universities, 15 rue Georges Clémenceau, 91406 Orsay Cedex, FranceDavid SarrutUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, FranceDennis R. SchaartDelft University of Technology, Radiation Detection & Medical Imaging, Mekelweg 15, 2629 JB Delft, The NetherlandsSimon StuteIMNC–UMR 8165 CNRS–Paris 7 and Paris 11 Universities, 15 rue Georges Clémenceau, 91406 Orsay Cedex, FranceU. PietrzykReseach Center Juelich, Institute of Neurosciences and Medicine and Department of Physics, University of Wuppertal, GermanyDimitris VisvikisINSERM, U650, Laboratoire du Traitement de l’Information Medicale (LaTIM), CHU Morvan, Brest, FranceN. ZahraUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, FranceIrène BuvatIMNC–UMR 8165 CNRS–Paris 7 and Paris 11 Universities, 15 rue Georges Clémenceau, 91406 Orsay Cedex, France
2011en
ABI

Аннотация

GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation platform developed by the OpenGATE collaboration since 2001 and first publicly released in 2004. Dedicated to the modelling of planar scintigraphy, single photon emission computed tomography (SPECT) and positron emission tomography (PET) acquisitions, this platform is widely used to assist PET and SPECT research. A recent extension of this platform, released by the OpenGATE collaboration as GATE V6, now also enables modelling of x-ray computed tomography and radiation therapy experiments. This paper presents an overview of the main additions and improvements implemented in GATE since the publication of the initial GATE paper (Jan et al 2004 Phys. Med. Biol. 49 4543-61). This includes new models available in GATE to simulate optical and hadronic processes, novelties in modelling tracer, organ or detector motion, new options for speeding up GATE simulations, examples illustrating the use of GATE V6 in radiotherapy applications and CT simulations, and preliminary results regarding the validation of GATE V6 for radiation therapy applications. Upon completion of extensive validation studies, GATE is expected to become a valuable tool for simulations involving both radiotherapy and imaging.

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