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Four New Diterpene Glucosides from <i>Perovskia atriplicifolia</i>

Lu GaoCollege of Life &amp; Environmental Sciences Minzu University of China Beijing 100081 P. R. ChinaJun ZhouKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaLe‐Yu ZhuKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaJuan‐Rong ZhangKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaYu‐Xing JingKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaJia‐Wen ZhaoKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaXiang‐Zhong HuangKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaGanpeng LiKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaZhi‐Yong JiangKey Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission &amp; Ministry of Education Yunnan Minzu University Kunming 650500 P. R. ChinaDa‐Yuan XueCollege of Life &amp; Environmental Sciences Minzu University of China Beijing 100081 P. R. China
2017en
ABI

Аннотация

Four new diterpene glucosides, namely perovskiaditerpenosides A - D (1 - 4), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated compounds were screened for their cytotoxic activity against HepG2, NB4, HeLa, K562, MCF7, PC3, and HL60. The obtained results indicated that the new compounds possessed considerable cytotoxic activity.

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