Статья

Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era

Salvatore De RosaDepartment of Medical and Surgical Sciences, Magna Graecia University , Catanzaro, ItalyCarmen SpaccarotellaDepartment of Medical and Surgical Sciences, Magna Graecia University , Catanzaro, ItalyCristina BassoCardiovascular Pathology Unit, University of Padua , Padua, ItalyMaria Pia CalabròDepartment of Human Pathology, University of Messina , Messina, ItalyAntonio CurcioDepartment of Medical and Surgical Sciences, Magna Graecia University , Catanzaro, ItalyPasquale Perrone FilardiDepartment of Advanced Biomedical Sciences, Federico II University , Naples and Mediterranea Cardiocentro, Naples ItalyMassimo ManconeItalian Society of Cardiology , Via Po 24, 00198 Rome, ItalyGiuseppe MercuroDepartment of Medical Sciences and Public Health, University of Cagliari , Cagliari, ItalySaverio MuscoliDepartment of Medicine, ‘Tor Vergata’ University of Rome , Rome, ItalySavina NodariDepartment of Cardiology, University of Brescia and ASST Spedali Civili di Brescia , Brescia, ItalyRoberto PedrinelliCardiac, Thoracic and Vascular Department, University of Pisa , Pisa, ItalyGianfranco SinagraCardiovascular Department, University of Trieste , Trieste, ItalyCiro IndolfiDepartment of Medical and Surgical Sciences, Magna Graecia University , Catanzaro, ItalyFilippo AngeliniFrancesco BarillàAntonio L. BartorelliDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyFrancesco BenedettoPaola BernabòLeonardo BologneseMartina BrianiLuisa CacciavillaniAlice CalabresePaolo CalabròDepartment of Human Pathology, University of Messina, Messina, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyLuigi CaliendoLeonardo CalòGianni CasellaGavino CasuClaudio CavalliniQuirino CiampiMarco Matteo CicconeMichele ComitoElena CorradaFilippo CreaAntonello D’AndreaMaurizio DʼUrbanoRaffaele De CaterinaGaetano Maria De FerrariRoberto De PontiCardiac, Thoracic and Vascular Department, University of Pisa, Pisa, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyAlessio Della MattiaCarlo Di MarioLuca DonazzanGiovanni EspositoFrancesco FedeleAlessandro FerraroGennaro GalassoNazzareno GalièMassimiliano GnecchiPaolo GolinoBruno GoliaPasquale GuariniCiro IndolfiDepartment of Medical and Surgical Sciences, Magna Graecia University , Catanzaro, ItalySergio LeonardiNicola LocuratoloFrancesco LuzzaVincenzo ManganielloMaria Francesca MarchettiDepartment of Human Pathology, University of Messina, Messina, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyGiancarlo MarenziAlberto MargonatoLuigi MeloniMarco MetraMarco MiloAnnalisa MongiardoLuca MonzoCarmine MoriscoGiuseppina NovoStefano PancaldiM ParolloGiovanni PaternòGiuseppe PattiDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalySilvia G. PrioriAmelia RaveraAntonio G. RebuzziDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyMassimo RossiItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy; Sapienza University of Rome, Rome, ItalyMarino ScherilloFranco SempriniCardiovascular Department, University of Trieste, Trieste, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyMichele SenniGerolamo SibilioMassimo SivigliaItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy; Sapienza University of Rome, Rome, ItalyCorrado TamburinoGianfranco TortoriciCardiovascular Department, University of Trieste, Trieste, Italy; Italian Society of Cardiology, Via Po 24, 00198 Rome, ItalyFrancesco VersaceBruno VillariMassimo VolpeItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy; Sapienza University of Rome, Rome, Italy

2020en

ABI

Аннотация

AIMS: To evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). METHODS AND RESULTS: We conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7-32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3-70.3; P < 0.001). Among STEMIs, the reduction was higher for women (41.2%; P = 0.011) than men (17.8%; P = 0.191). A similar reduction in AMI admissions was registered in North Italy (52.1%), Central Italy (59.3%), and South Italy (52.1%). The STEMI case fatality rate during the pandemic was substantially increased compared with 2019 [risk ratio (RR) = 3.3, 95% CI 1.7-6.6; P < 0.001]. A parallel increase in complications was also registered (RR = 1.8, 95% CI 1.1-2.8; P = 0.009). CONCLUSION: Admissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates. This constitutes a serious social issue, demanding attention by the scientific and healthcare communities and public regulatory agencies.

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Идентификаторы

DOI: 10.1093/eurheartj/ehaa409

Цитирования и источники

Цитирований: 2Использованных источников: 0

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