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Antibacterial Activity and Composition of the Essential Oil of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech. f. from Iran

Ali SonboliDepartment of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, P.O. Box 19835-389, Tehran, Iran. Fax: (+98-21)22418679Mohammad Hossein MirjaliliDepartment of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, IranJavad HadianDepartment of Horticulture, Faculty of Horticulture and Plant Protection, University of Tehran, Karaj, IranSamad Nejad EbrahimiDepartment of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, IranMorteza YousefzadiDepartment of Ecology & Systematic, Research Institute of Applied Sciences, ACECR, Evin, Tehran, Iran
2006en
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Аннотация

The chemical composition of the essential oil obtained from the aerial flowering parts of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech. f. was analyzed by GC and GC-MS. Thirty-two components representing 97.1% of the total oil were identified. Oxygenated monoterpenes (94.3%) were the predominant fraction of the oil with pulegone (65.2%), isomenthone (11.9%), 1,8-cineole (7.8%) and piperitenone (6.5%) as the main constituents. Antibacterial activity of the oil and also its two main components (pulegone and 1,8-cineole) were tested against seven bacteria. It was found that the oil exhibited interesting antibacterial activity against Staphylococcus epidermidis, S. aureus, Escherichia coli and Bacillus subtilis with MIC values of 3.75 mg/ml.

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