Escins-Ia, Ib, IIa, IIb, and IIIa, Bioactive Triterpene Oligoglycosides from the Seeds of Aesculus hippocastanum L.: Their Inhibitory Effects on Ethanol Absorption and Hypoglycemic Activity on Glucose Tolerance Test.
Masayuki YoshikawaKyoto Pharmaceutical University, JapanEmiko HaradaKyoto Pharmaceutical University, Kyoto, JapanToshiyuki MurakamiKyoto Pharmaceutical University, Kyoto, JapanHisashi MatsudaKyoto Pharmaceutical University, Kyoto, JapanNoriko WariishiKyoto Pharmaceutical University, Kyoto, JapanJohji YamaharaKyoto Pharmaceutical University, Kyoto, JapanNobutoshi MurakamiKyoto Pharmaceutical University, Kyoto, JapanIsao KitagawaKyoto Pharmaceutical University, Kyoto, Japan
1994en
ABI
Аннотация
Five triterpene oligoglycosides named escins-Ia, Ib, IIa, IIb, and IIIa were isolated from the seeds of Aesculus hippocastanum L. and their chemical structures were determined on the basis of chemical and physicochemical evidence. Escins-Ia, Ib, IIa, and IIb were found to exhibit inhibitory effect on ethanol absorption and hypoglycemic activity on oral glucose tolerance test in rats. Among them, escins-IIa and IIb showed the higher activities for both bioassays, while desacylescins-I and II had no activity.
Перевод пока недоступен
Идентификаторы
Цитирования и источники
Цитирований: 5Использованных источников: 0