Статья

Simple fluorescence optosensing probe for spermine based on ciprofloxacin-Tb3+ complexation

Nguyen Ngoc NghiaDepartment of Materials Convergence and System Engineering, Changwon National University, Changwon, Republic of KoreaBui The HuyDepartment of Materials Convergence and System Engineering, Changwon National University, Changwon, Republic of KoreaP.T. PhongCeramics and Biomaterials Research Group, Advanced Institute of Materials Science, Ton Duc Thang University, Ho Chi Minh City, Viet NamJin Sol HanDepartment of Materials Convergence and System Engineering, Changwon National University, Changwon, Republic of KoreaDae Hyun KwonDepartment of Materials Convergence and System Engineering, Changwon National University, Changwon, Republic of KoreaYong‐Ill LeeCeramics and Biomaterials Research Group, Advanced Institute of Materials Science, Ton Duc Thang University, Ho Chi Minh City, Viet Nam

2021en

ABI

Аннотация

We developed a facile detection method of spermine based on the fluorescence (FL) quenching of the ciprofloxacin-Tb3+ complex, which shows astrong green emission. Ciprofloxacin (CP) makes efficient bondings to Tb3+ ion as a linker molecule through carboxylic and ketone groups to form a kind of lanthanide coordination polymer. The addition of spermine that competes with Tb3+ ions for the interaction with CP due to its positive charge brings about weakened coordination linkage of CP and Tb3+. The probe exhibited high sensitivity, selectivity, and good linearity in the range of 2-180 μM with a low limit of detection of 0.17 μM. Moreover, we applied this method on the paper strip test (PST), along with the integration of a smartphone and Arduino-based device. The practical reliability of the developed probe was evaluated on human serum samples with acceptable analytical results.

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Идентификаторы

DOI: 10.1371/journal.pone.0251306

Цитирования и источники

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