Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility
Lewis D. BlackmanDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United KingdomSpyridon VarlasDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United KingdomMaria C. ArnoDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United KingdomZachary H. HoustonARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of Queensland, St. Lucia, Queensland 4072, AustraliaNicholas L. FletcherARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of Queensland, St. Lucia, Queensland 4072, AustraliaKristofer J. ThurechtARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of Queensland, St. Lucia, Queensland 4072, AustraliaMuhammad HasanDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United KingdomMatthew I. GibsonDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United KingdomRachel K. O’ReillyDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL Coventry, United Kingdom
2018en
ABI
Аннотация
was compared to the free enzyme, highlighting this methodology as an attractive alternative to the covalent PEGylation of enzymes.
Перевод пока недоступен
Идентификаторы
Цитирования и источники
Цитирований: 2Использованных источников: 0