Статья

Bioactive Profiles, Antioxidant Activities, Nitrite Scavenging Capacities and Protective Effects on H2O2-Injured PC12 Cells of Glycyrrhiza Glabra L. Leaf and Root Extracts

Yi DongCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaMouming ZhaoCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaTiantian ZhaoCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaMengying FengCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaHuiping ChenCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaMingzhu ZhuangCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, ChinaLianzhu LinCollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, China

2014en

ABI

Аннотация

This study compared the total flavonoid content of Glycyrrhiza glabra L. leaf and root extracts. Results suggested that the total flavonoid content in the leaf extract was obviously higher than that in the root extract. Pinocembrin, the main compound in the leaf extract after purification by column chromatography, showed good antioxidant activity and nitrite scavenging capacity, but moderate inhibitory effect on mushroom tyrosinase. Liquiritin was the main compound in root extract and possessed strong inhibitory effect on mushroom tyrosinase. Both compounds exhibited significant protection effect on H2O2-injured PC12 cells at a low concentration. These results indicate that Glycyrrhiza glabra L. leaf is potential as an important raw material for functional food.

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Идентификаторы

DOI: 10.3390/molecules19079101

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar