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Solid dispersions, Part I: recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

Dimitrios Ν. BikiarisAristotle University of Thessaloniki, Department of Chemistry, Laboratory of Polymer Chemistry and Technology, GR-541 24 Thessaloniki, [email protected]
2011en
ABI

Аннотация

Introduction: In recent years, the number of active pharmaceutical ingredients with high therapeutic impact, but very low water solubility, has increased significantly. Thus, a great challenge for pharmaceutical technology is to create new formulations and efficient drug-delivery systems to overcome these dissolution problems.

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