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Microfluidic Paper-Based Analytical Devices: From Design to Applications

Eka NovianaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia 55281Tuğba ÖzerDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey 34220Cody S. CarrellDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United StatesJeremy LinkDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United StatesCatherine McMahonDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United StatesIlhoon JangDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United StatesCharles S. HenryDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States
2021en
ABI

Аннотация

Microfluidic paper-based analytical devices (μPADs) have garnered significant interest as a promising analytical platform in the past decade. Compared with traditional microfluidics, μPADs present unique advantages, such as easy fabrication using established patterning methods, economical cost, ability to drive and manipulate flow without equipment, and capability of storing reagents for various applications. This Review aims to provide a comprehensive review of the field, highlighting fabrication methods available to date with their respective advantages and drawbacks, device designs and modifications to accommodate different assay needs, detection strategies, and the growing applications of μPADs. Finally, we discuss how the field needs to continue moving forward to realize its full potential.

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