Glaucoma and Antioxidants: Review and Update
José Javier García‐MedinaDepartment of Ophthalmology and Optometry, University of Murcia, 30120 Murcia, SpainElena Rubio-VelázquezDepartment of Ophthalmology, General University Hospital Morales Meseguer, 30008 Murcia, SpainMaría Dolores López-BernalDepartment of Ophthalmology, General University Hospital Morales Meseguer, 30008 Murcia, SpainAlejandro Cobo-MartinezDepartment of Ophthalmology, General University Hospital Morales Meseguer, 30008 Murcia, SpainVicente Zanón‐MorenoArea of Health Sciences, Valencian International University, 46002 Valencia, SpainM.D. Pinazo-DuránDepartment of Ophthalmology, University of Valencia, 46010 Valencia, SpainMónica del‐Río‐VellosilloDepartment of Anesthesiology, University Hospital Virgen de la Arrixaca, 30120 Murcia, Spain
2020en
ABI
Аннотация
Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of retinal ganglion cells. Oxidative stress has been related to the cell death in this disease. Theoretically, this deleterious consequence can be reduced by antioxidants substances. The aim of this review is to assemble the studies published in relation to antioxidant supplementation and its effects on glaucoma and to offer the reader an update on this field. With this purpose, we have included studies in animal models of glaucoma and clinical trials. Although there are variable results, supplementation with antioxidants in glaucoma may be a promising therapy in glaucoma.
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