Статья

THE GEANT4-DNA PROJECT

S. IncertiUniversité Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, FranceGérard BaldacchinoCEA Saclay, IRAMIS, UMR3299 CEA-CNRS SIS2M, Laboratoire de Radiolyse, F-91191 Gif-sur-Yvette Cedex, FranceMario A. BernalDepartamento de Física, Universidad Simon Bolívar, VenezuelaR. CapraC. ChampionZ. FrancisIRSN, Institut de Radioprotection et de Sureté Nucléaire, BP17, 92262 Fontenay-aux-Roses, FranceP. GuèyeHampton University, Physics Department, Hampton VA 23668, USAA. ManteroUniversité Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, FranceB. MascialinoKarolinska Institutet, Box 260, S-171-76, Stockholm, SwedenPhilippe MorettoUniversité Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, FranceP. NieminenESA-ESTEC, 2200 AG Noordwijk, The NetherlandsC. VillagrasaIRSN, Institut de Radioprotection et de Sureté Nucléaire, BP17, 92262 Fontenay-aux-Roses, FranceC. Zacharatou

2010en

ABI

Аннотация

The Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionizing radiations at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of the deleterious effects of radiations that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole on-going project, including its most recent developments that are available in the Geant4 toolkit since December 2009 (release 9.3), as well as an illustration example simulating the direct irradiation of a biological chromatin fiber. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdisciplinary activity of the Geant4 collaboration are also discussed.

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Идентификаторы

DOI: 10.1142/s1793962310000122

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar