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Carbon Dots as Promising Tools for Cancer Diagnosis and Therapy

Giuseppe NocitoDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, ItalyGiovanna CalabreseDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, ItalyStefano ForteSalvatore PetraliaDepartment of Drug Science and Health, University of Catania, 95125 Catania, ItalyCaterina PuglisiMichela CampoloDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, ItalyEmanuela EspositoDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, ItalySabrina ConociDepartment of Chemistry, Biology, Pharmacy and Environmental Science, University of Messina, 98122 Messina, Italy
2021en
ABI

Аннотация

Carbon Dots (CDs) are the latest members of carbon-based nanomaterials, which since their discovery have attracted notable attention due to their chemical and mechanical properties, brilliant fluorescence, high photostability, and good biocompatibility. Together with the ease and affordable preparation costs, these intrinsic features make CDs the most promising nanomaterials for multiple applications in the biological field, such as bioimaging, biotherapy, and gene/drug delivery. This review will illustrate the most recent applications of CDs in the biomedical field, focusing on their biocompatibility, fluorescence, low cytotoxicity, cellular uptake, and theranostic properties to highlight above all their usefulness as a promising tool for cancer diagnosis and therapy.

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