Обзорная статья

Gold Nanoparticles in Nanobiotechnology: From Synthesis to Biosensing Applications

Arun KarnwalSchool of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaRohan Samir Kumar SachanSchool of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaInderpal DevgonSchool of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, Punjab, IndiaJyotsna DevgonCentre for Interdisciplinary Biomedical Research, Adesh University, Bathinda 151101, Punjab, IndiaGaurav PantDepartment of Microbiology, Graphic Era (Deemed to be University), Dehradun 248009, Uttarakhand, IndiaMitali PanchpuriSchool of Pharmaceutical and Population Health Informatics, DIT University, Dehradun 248009, Uttarakhand, IndiaAkil AhmadDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi ArabiaMohammed B. AlshammariDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi ArabiaKaizar HossainDepartment of Environmental Science, Asutosh College, University of Calcutta, 92, Shyama Prasad Mukherjee Rd, Bhowanipore, Kolkata 700026, West Bengal, IndiaGaurav KumarSchool of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, Punjab, India

2024en

ABI

Аннотация

Nanobiotechnology has ushered in a new era of scientific discovery where the unique properties of nanomaterials, such as gold nanoparticles, have been harnessed for a wide array of applications. This review explores gold nanoparticles' synthesis, properties, and multidisciplinary applications, focusing on their role as biosensors. Gold nanoparticles possess exceptional physicochemical attributes, including size-dependent optical properties, biocompatibility, and ease of functionalization, making them promising candidates for the development of biosensing platforms. The review begins by providing a comprehensive overview of gold nanoparticle synthesis techniques, highlighting the advantages and disadvantages of various approaches. It then delves into the remarkable properties that underpin their success in biosensing, such as localized surface plasmon resonance and enhanced surface area. The discussion also includes the functionalization strategies that enable specific binding to biomolecules, enhancing the sensitivity and selectivity of gold-nanoparticle-based biosensors. Furthermore, this review surveys the diverse applications of gold nanoparticles in biosensing, encompassing diagnostics, environmental monitoring, and drug delivery. The multidisciplinary nature of these applications underscores the versatility and potential of gold nanoparticles in addressing complex challenges in healthcare and environmental science. The review emphasizes the pressing need for further exploration and research in the field of nanobiotechnology, particularly regarding the synthesis, properties, and biosensing applications of gold nanoparticles. With their exceptional physicochemical attributes and versatile functionalities, gold nanoparticles present a promising avenue for addressing complex challenges in healthcare and environmental science, making it imperative to advance our understanding of their synthesis, properties, and applications for enhanced biosensing capabilities and broader scientific innovation.

Перевод пока недоступен

Идентификаторы

DOI: 10.1021/acsomega.3c10352

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar