Ligand efficiency as a guide in fragment hit selection and optimization
Sabine SchultesBoehringer Ingelheim RCV GmbH & Co. KG, Department of Medicinal Chemistry, Dr. Boehringer-Gasse 5-11, Vienna, AustriaChris de GraafLeiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Department of Pharmacochemistry, Faculty of Exact Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The NetherlandsEric HaaksmaBoehringer Ingelheim RCV GmbH & Co. KG, Department of Medicinal Chemistry, Dr. Boehringer-Gasse 5-11, Vienna, AustriaIwan J. P. de EschLeiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Department of Pharmacochemistry, Faculty of Exact Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The NetherlandsRob LeursLeiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Department of Pharmacochemistry, Faculty of Exact Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The NetherlandsOliver KrämerBoehringer Ingelheim RCV GmbH & Co. KG, Department of Medicinal Chemistry, Dr. Boehringer-Gasse 5-11, Vienna, Austria
2010en
ABI
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