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The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes

Jing LiangCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, ChinaYiwen HeHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, ChinaChunxia HuangSchool of Stomatology, Changsha Medical University, Changsha 410219, ChinaFengjie JiTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, ChinaXihong ZhouCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, ChinaYulong YinCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, ChinaYulong YinCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, China
2024en
ABI

Аннотация

Selenium is an essential micronutrient required for the synthesis and function of selenoproteins, most of which are enzymes involved in maintaining oxidative balance in the body. Diabetes is a group of metabolic disorders characterized by high blood glucose levels over a prolonged period of time. There are three main types of diabetes: type 1, type 2, and gestational diabetes. This review summarizes recent advances in the field of diabetes research with an emphasis on the roles of selenoproteins on metabolic disturbance in diabetes. We also discuss the interaction between selenoproteins and glucose and lipid metabolism to provide new insights into the prevention and treatment of diabetes.

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