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Review of MXene-Derived Quantum Dots for Cancer Theranostics

Yanlin ZhuKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. ChinaLili FengKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. ChinaRuoxi ZhaoKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. ChinaBin LiuKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. ChinaPiaoping YangKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China
2024en
ABI

Аннотация

The two-dimensional MXenes quantum dots (2D-MQDs) integrate the characteristics of 2D MXenes with quantum dots, exhibiting the characteristics of unique optical properties, manifold functionalization, good biocompatibility, satisfactory dispersibility, and so on. The excellent performances of 2D-MQDs endow them with extensive application prospects for catalysis, sensing, and biomedical applications. However, to date, there is no review paper on 2D-MQDs for imaging and cancer therapy. In this Review, our purpose is to offer a comprehensive summary of progress in the synthesis (traditional and the latest top-down and bottom-up methods) and modification (surface functionalization, doping, and heterostructures) of 2D-MQDs. In addition, the focus then turns to the applications in bioimaging (luminescent-based imaging, photoacoustic imaging, and magnetic resonance imaging) and cancer therapy (photothermal therapy, sonodynamic therapy, immunotherapy, and catalytic therapy) of 2D-MQDs. Finally, future perspectives of the 2D-MQDs are proposed to promote their further development in cancer diagnosis and treatment. This Review will give assistance to comprehend the comprehensive and advanced development of 2D-MQDs, which could not only provide suggestions for the future design of 2D-MQDs in cancer theranostics, but also boost the other applications of 2D-MQDs to satisfy the growing requirements.

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