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Antibiotic resistance: a rundown of a global crisis

Bilal AslamDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanWei WangNHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, ChinaMuhammad ArshadInstitute of Microbiology, University of Agriculture Faisalabad, Faisalabad, PakistanMohsin KhurshidCollege of Allied Health Professionals, Directorate of Medical Sciences, Government College University Faisalabad, Faisalabad, PakistanSaima MuzammilDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanMuhammad Hidayat RasoolDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanMuhammad Atif NisarDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanRuman Farooq AlviDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanMuhammad Aamir AslamInstitute of Microbiology, University of Agriculture Faisalabad, Faisalabad, PakistanMuhammad Usman QamarDepartment of Microbiology, Government College University Faisalabad, Faisalabad, PakistanMuhammad Khalid Farooq SalamatNeurobiology Division, The Roslin Institute, University of Edinburgh, Edinburgh, UKZulqarnain BalochCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China, [email protected]
2018en
ABI

Аннотация

The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and due to unavailability of newer drugs attributable to exigent regulatory requirements and reduced financial inducements. Comprehensive efforts are needed to minimize the pace of resistance by studying emergent microorganisms, resistance mechanisms, and antimicrobial agents. Multidisciplinary approaches are required across health care settings as well as environment and agriculture sectors. Progressive alternate approaches including probiotics, antibodies, and vaccines have shown promising results in trials that suggest the role of these alternatives as preventive or adjunct therapies in future.

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