Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial
Melinda HamerWalter Reed Army Institute of Research, Silver Spring, MD, USA; Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USAKatherine V. HouserVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address: [email protected]Amelia R. HofstetterVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAAna M. Ortega‐VillaBiostatistics Research Branch, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAChristine LeeWalter Reed Army Institute of Research, Silver Spring, MD, USAAnne PrestonWalter Reed Army Institute of Research, Silver Spring, MD, USABrooke AugustineWalter Reed Army Institute of Research, Silver Spring, MD, USACharla AndrewsVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAGalina V. YamshchikovVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USASomia P. HickmanVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USASteven SchechHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USAJack HutterWalter Reed Army Institute of Research, Silver Spring, MD, USAPaul T. ScottWalter Reed Army Institute of Research, Silver Spring, MD, USAPaige WatermanWalter Reed Army Institute of Research, Silver Spring, MD, USAMihret F. AmareHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USAVictoria KiokoHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USACasey StormeHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USAKayvon ModjarradWalter Reed Army Institute of Research, Silver Spring, MD, USAMelanie McCauleyHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USAMerlin L. RobbHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USAMartin R. GaudinskiVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAIngelise J. GordonVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USALaSonji A. HolmanVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAAlicia T. WidgeVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USALarisa StromVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAMyra HappeVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAJosephine H. CoxVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USASandra VazquezVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USADaphne A. StanleyVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USATamar MurrayVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USACaitlyn N M DulanVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USARuth HunegnawVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USASandeep NarpalaVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAPhillip A. SwansonVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAManjula BasappaVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAJagada ThillainathanVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAMarcelino PadillaVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USABritta FlachVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USASarah O’ConnellVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAOlga TrofymenkoVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAPatricia MorganVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAEmily E. CoatesVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAJason G. GallVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAAdrian B. McDermottVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USARichard A. KoupVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAJohn R. MascolaVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAAurélie PloquinVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USANancy J. SullivanVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAJulie A. AkeWalter Reed Army Institute of Research, Silver Spring, MD, USAJulie E. LedgerwoodVaccine Research Center, and Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USARebecca LampleyBrenda LarkinPamela CostnerHope WilsonMike Read
2023en
ABI
Аннотация
Аннотация отсутствует.
Идентификаторы
Цитирования и источники
Цитирований: 2Использованных источников: 0