Alkaloids Produced by Endophytic Fungi: A Review
Yanyan ZhangAcademy of Integrative, Fujian University of Traditional Chinese Medicine, Fujian 350003, P.R. ChinaTing HanDepartment of, Pharmacognosy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, P.R. ChinaQianliang MingDepartment of, Pharmacognosy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, P.R. ChinaLingshang WuDepartment of, Pharmacognosy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, P.R. ChinaKhalid RahmanFaculty of Science, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UKLuping QinAcademy of Integrative, Fujian University of Traditional Chinese Medicine, Fujian 350003, P.R. China
2012en
ABI
Аннотация
In recent years, a number of alkaloids have been discovered from endophytic fungi in plants, which exhibited excellent biological properties such as antimicrobial, insecticidal, cytotoxic, and anticancer activities. This review mainly deals with the research progress on endophytic fungi for producing bioactive alkaloids such as quinoline and isoquinoline, amines and amides, indole derivatives, pyridines, and quinazolines. The biological activities and action mechanisms of these alkaloids from endophytic fungi are also introduced. Furthermore, the relationships between alkaloid-producing endophytes and their host plants, as well as their potential applications in the future are discussed.
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