A new C<sub>20</sub>-diterpenoid alkaloid from <i>Aconitum soongaricum</i> var. <i>pubescens</i>
Lin ChenKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaLianhai ShanSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaWenliang XuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaJifa ZhangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaShuai HuangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaXian‐Li ZhouKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, China
2016en
ABI
Аннотация
-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum soongaricum var. pubescens. Their structures were elucidated by means of extensive spectroscopic analyses (NMR and HR-ESI-MS) and comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against H460, MCF-7 and Hep G2 human cancer cell lines.
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