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Tools and techniques for solvent selection: green solvent selection guides

Fergal P. ByrneGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKSaimeng JinGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKGiulia PaggiolaGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKTabitha H. M. PetcheyGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKJames H. ClarkGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKThomas J. FarmerGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKAndrew J. HuntGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKCon Robert McElroyGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKJames SherwoodGreen Chemistry Centre of Excellence, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK
2016en
ABI

Аннотация

Driven by legislation and evolving attitudes towards environmental issues, establishing green solvents for extractions, separations, formulations and reaction chemistry has become an increasingly important area of research. Several general purpose solvent selection guides have now been published with the aim to reduce use of the most hazardous solvents. This review serves the purpose of explaining the role of these guides, highlighting their similarities and differences. How they can be used most effectively to enhance the greenness of chemical processes, particularly in laboratory organic synthesis and the pharmaceutical industry, is addressed in detail.

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