Diterpenoid Alkaloids from <i>Aconitum soongaricum</i> var. <i>pubescens</i>
Lin ChenKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaLianhai ShanSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaJifa ZhangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaWenliang XuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaMingyu WuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaShuai HuangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 ChinaXian‐Li ZhouKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031 China
2015en
ABI
Аннотация
One new diterpenoid alkaloid, pubescensine (1), along with nine known diterpenoid alkaloids (2-10) were isolated from the roots of Aconitum soongaricum var. pubescens. Their structures were elucidated by spectroscopic analyses and comparison with previously reported data. All the compounds were evaluated for their antifeedant activities. The aconitine-type diterpenoid alkaloids (1-6) showed considerably potent antifeedant activity (EC50 < 1 mg/cm2), while the activities of napelline-type diterpenoid alkaloids (compds. 7, 9 and 10) were not significant (EC50 > 50 mg/cm2).
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