Обзорная статья

An Overview of Meningiomas

Robin BuerkiDepartment of Neurological Surgery, University of California San Francisco, 400 Parnassus Ave., San Francisco, CA94143, USACraig HorbinskiDepartment of Pathology, Northwestern University, IL60611, USATim J. KruserDepartment of Radiation Oncology, Northwestern University, IL60611, USAPeleg HorowitzSection of Neurosurgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL60637, USAC. David JamesDepartment of Neurosurgery, Northwestern University, IL60611, USARimas V. LukasDepartment of Neurology, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1114, Chicago, IL60611, USA

2018en

ABI

Аннотация

Meningiomas are the most common primary intracranial tumor. Important advances are occurring in meningioma research. These are expected to accelerate, potentially leading to impactful changes on the management of meningiomas in the near and medium term. This review will cover the histo- and molecular pathology of meningiomas, including recent 2016 updates to the WHO classification of CNS tumors. We will discuss clinical and radiographic presentation and therapeutic management. Surgery and radiotherapy, the two longstanding primary therapeutic modalities, will be discussed at length. In addition, data from prior and ongoing investigations of other treatment modalities, including systemic and targeted therapies, will be covered. This review will quickly update the reader on the contemporary management and future directions in meningiomas. [Formula: see text].

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Идентификаторы

DOI: 10.2217/fon-2018-0006

Цитирования и источники

Цитирований: 2Использованных источников: 0

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