Enhancing Efficiency and Sustainability: Unleashing the Potential of Continuous Flow in Multicomponent Reactions
Marcelo H. R. CarvalhoDepartment of Chemistry Federal University of Juiz de Fora Rua José Lourenço Kelmer, s/n - São Pedro Juiz de Fora - MG 36036–900 BrazilPedro P. de CastroDepartment of Pharmacy Federal University of Juiz de Fora – Campus Governador Valadares Rua Manoel Byrro, 241 – Vila Bretas Governador Valadares - MG 35032–620 BrazilKleber T. de OliveiraDepartment of Chemistry Federal University of São Carlos Rod. Washington Luís, s/n - Monjolinho São Carlos - SP 13565–905 BrazilKleber T. de OliveiraDepartment of Chemistry Federal University of São Carlos Rod. Washington Luís, s/n - Monjolinho São Carlos - SP 13565–905 BrazilGiovanni W. AmaranteDepartment of Chemistry Federal University of Juiz de Fora Rua José Lourenço Kelmer, s/n - São Pedro Juiz de Fora - MG 36036–900 Brazil
2024en
ABI
Аннотация
The integration of multicomponent reactions (MCRs), which offer a rapid and efficient approach to synthesize complex molecular scaffolds, with continuous flow platforms is an increasingly recognized strategy in green synthesis. This association enables precise control over reaction parameters, including improved kinetics and selectivity, reduced reaction times, enhanced yields and scalabilities, while aligning with sustainable and green chemistry principles through resource utilization, minimized waste, and reduced environmental impact. This review presents a critical analysis of recent studies covering the MCR-continuous flow association, with a focus on achieving greener and more sustainable synthesis practices.
Перевод пока недоступен
Идентификаторы
Цитирования и источники
Цитирований: 2Использованных источников: 0