Статья

Activatable fluorescent probes for imaging and diagnosis of hepatocellular carcinoma

Xiaoxiao MenDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. ChinaFanghong LiuSchool of Elderly Welfare, China Civil Affairs University, Beijing 102600, P. R. ChinaMingyue GongDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. ChinaXuchao WangDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. ChinaLing WangHunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha Medical University, Changsha, Hunan 410219, P. R. ChinaXiaoju MenDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. ChinaHaobin ChenDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. ChinaZhuxin DongDepartment of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013, P. R. China

2024en

ABI

Аннотация

Liver cancer, specifically hepatocellular carcinoma (HCC), is a malignant neoplasm of the digestive system, characterized by exceptionally high morbidity and mortality rates on a global scale. Early detection and diagnosis are critical measures for enhancing the prognosis of patients diagnosed with HCC. An improved prognosis is significantly reliant on the timely diagnosis of the disease and effective therapeutic monitoring. Activatable fluorescent probes are essential for detecting and imaging biomarkers related to disease diagnosis and in vivo imaging. This paper reviews the fluorescent probes developed over the past five years for the detection and imaging of HCC. This noninvasive optical imaging modality demonstrates significant promise in targeting pathological sites and is anticipated to facilitate potential clinical translation.

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Идентификаторы

DOI: 10.1142/s1793545825300046

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar