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High‐Fidelity Bioelectrodes with Bidirectional Ion–Electron Transduction Capability by Integrating Multiple Charge‐Transfer Processes

Rongjian HuSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaBowen YaoSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaYuhao GengSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaShuai ZhouSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaMengfan LiState Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Sciences and Biomedical Engineering Hebei University of Technology Tianjin 300132 P. R. ChinaWei ZhongSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaFuyao SunSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaHaojie ZhaoSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaJingyu WangState Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Sciences and Biomedical Engineering Hebei University of Technology Tianjin 300132 P. R. ChinaJiahao GeState Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Sciences and Biomedical Engineering Hebei University of Technology Tianjin 300132 P. R. ChinaRan WeiState Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Sciences and Biomedical Engineering Hebei University of Technology Tianjin 300132 P. R. ChinaTong LiuSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaJiajie JinSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaJian‐Hua XuSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. ChinaJiajun FuSchool of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 P. R. China
2024en
ABI

Аннотация

Bioelectronics is an exciting field that bridges the gap between physiological activities and external electronic devices, striving for high resolution, high conformability, scalability, and ease of integration. One crucial component in bioelectronics is bioelectrodes, designed to convert neural activity into electronic signals or vice versa. Previously reported bioelectrodes have struggled to meet several essential requirements simultaneously: high-fidelity signal transduction, high charge injection capability, strain resistance, and multifunctionality. This work introduces a novel strategy for fabricating superior bioelectrodes by merging multiple charge-transfer processes. The resulting bioelectrodes offer accurate ion-to-electron transduction for capturing electrophysiological signals, dependable charge injection capability for neuromodulation, consistent electrode potential for artifact rejection and biomolecule sensing, and high transparency for seamless integration with optoelectronics. Furthermore, the bioelectrode can be designed to be strain-insensitive by isolating signal transduction from electron transportation. The innovative concept presented in this work holds great promise for extending to other electrode materials and paves the way for the advancement of multimodal bioelectronics.

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