Обзорная статья

Influence of diet on the gut microbiome and implications for human health

Rasnik SinghUniversity of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USAHsin-Wen ChangDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USADi YanDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USAKristina M. LeeDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USADerya UçmakDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USAKirsten WongDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USAMichael AbroukUniversity of California, Irvine, School of Medicine, Irvine, CA, 92697, USABenjamin FarahnikUniversity of Vermont College of Medicine, Burlington, VT, 05405, USAMio NakamuraDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USATian Hao ZhuUniversity of Southern California Keck School of Medicine, Los Angeles, CA, 90033, USATina BhutaniDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USAWilson LiaoDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA. [email protected]

2017en

ABI

Аннотация

Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer. At the same time, it is now understood that diet plays a significant role in shaping the microbiome, with experiments showing that dietary alterations can induce large, temporary microbial shifts within 24 h. Given this association, there may be significant therapeutic utility in altering microbial composition through diet. This review systematically evaluates current data regarding the effects of several common dietary components on intestinal microbiota. We show that consumption of particular types of food produces predictable shifts in existing host bacterial genera. Furthermore, the identity of these bacteria affects host immune and metabolic parameters, with broad implications for human health. Familiarity with these associations will be of tremendous use to the practitioner as well as the patient.

Перевод пока недоступен

Идентификаторы

DOI: 10.1186/s12967-017-1175-y

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar