Статья

Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA

Marina BikchurinaBudker Institute of Nuclear Physics, Novosibirsk, RussiaT. A. BykovBudker Institute of Nuclear Physics, Novosibirsk, RussiaIbrahim IbrahimBudker Institute of Nuclear Physics, Novosibirsk, RussiaА. I. KasatovaBudker Institute of Nuclear Physics, Novosibirsk, RussiaD. A. KasatovBudker Institute of Nuclear Physics, Novosibirsk, RussiaIaroslav KolesnikovBudker Institute of Nuclear Physics, Novosibirsk, RussiaVictoria KonovalovaBudker Institute of Nuclear Physics, Novosibirsk, RussiaTimur KormushakovBudker Institute of Nuclear Physics, Novosibirsk, RussiaAlexey KoshkarevBudker Institute of Nuclear Physics, Novosibirsk, RussiaАнтон Александрович КузнецовBudker Institute of Nuclear Physics, Novosibirsk, RussiaV.V. PorosevBudker Institute of Nuclear Physics, Novosibirsk, RussiaС. С. СавиновBudker Institute of Nuclear Physics, Novosibirsk, RussiaIvan ShchudloBudker Institute of Nuclear Physics, Novosibirsk, RussiaN. Sh. SingatulinaBudker Institute of Nuclear Physics, Novosibirsk, RussiaEvgeniia SokolovaBudker Institute of Nuclear Physics, Novosibirsk, RussiaТ. V. SychevaBudker Institute of Nuclear Physics, Novosibirsk, RussiaIuliia TaskaevaBudker Institute of Nuclear Physics, Novosibirsk, RussiaG. D. VerkhovodBudker Institute of Nuclear Physics, Novosibirsk, RussiaS. Yu. TaskaevBudker Institute of Nuclear Physics, Novosibirsk, Russia

2023en

ABI

Аннотация

The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s response to treatment is becoming relevant. In this work, a number of dosimetric techniques have been developed: a compact neutron detector with a pair of cast scintillators, one of which is enriched with boron, to measure the boron dose and the γ-ray dose; cell dosimeter for measuring the sum of the equivalent dose of fast neutrons and the equivalent nitrogen dose; prompt γ-ray spectroscopy for in situ measurement of boron dose in real time; epithermal neutron flux monitor for measuring the epithermal neutron flux. Their verification carried out on the accelerator based neutron source VITA showed that they can become convenient and reliable tools for characterization of neutron beam and assessing the patient’s response to treatment.

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Идентификаторы

DOI: 10.3389/fnuen.2023.1266562

Цитирования и источники

Цитирований: 3Использованных источников: 0

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