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The Chemical Composition and Biological Activity of the Essential Oil from the Underground Parts of Ferula tadshikorum (Apiaceae)

Farukh SharopovDepartment of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, 734003, Dushanbe, TajikistanPayrav D. KhalifaevDepartment of Pharmaceutical Technology and Biotechnology, National University of Tajikistan, Rudaki 17/3, 734003, Dushanbe, TajikistanPrabodh SatyalAromatic Plant Research Center, 615 St. George Square Court, Suite 300, Winston-Salem, NC 27103, USAYanfang SunCollege of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, ChinaAbduahad SafomuddinFaculty of Chemistry, National University of Tajikistan, Rudaki 17/2, 734003, Dushanbe, TajikistanСафол МусозодаDepartment of Pharmaceutical Technology and Biotechnology, National University of Tajikistan, Rudaki 17/3, 734003, Dushanbe, TajikistanMichaël WinkInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, Heidelberg 69120, GermanyWilliam N. SetzerAromatic Plant Research Center, 615 St. George Square Court, Suite 300, Winston-Salem, NC 27103, USA
2018en
ABI

Аннотация

The underground parts of Ferula tadshikorum M. Pimen were collected from the southern part of Tajikistan. The essential oils were obtained by hydrodistillation and analyzed by GLC-FID and GLC-MS. A total of 26 compounds were identified representing 94.4 % of total oil composition. The essential oil was dominated by the sulfur-containing compounds (Z)-1-propenyl sec-butyl disulfide (37. 3%), (E)-1-propenyl secbutyl disulfide (29.9%), (E)-1-propenyl 1-(methylthio)propyl disulfide (16.8%), and propyl sec-butyl disulfide (4.8%). The antioxidant, antimicrobial and cytotoxic activities of the essential oil was evaluated. To our best knowledge, this is the first report concerning the chemical composition and biological activity of the essential oil obtained from the underground parts of F. tadshikorum.

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